trophon2 is the Global Standard of Care ultrasound reprocessing.

trophon®2 is the Global Standard of Care for ultrasound probe reprocessing

As a market leader in automated reprocessing systems, Nanosonics’ trophon® technology* is the global standard in ultrasound probe reprocessing that helps protect patients by delivering consistent High Level Disinfection (HLD) with every automated cycle. trophon®2 is manufactured in Australia and with an expanding global network in 21 countries and an established global supply chain, Nanosonics is well placed to continue to provide unparalleled service and supply.

As a fully enclosed automated reprocessing system, leveraging chemistry and technology, trophon2 offers the reliability you need with a workflow efficiency that may surprise you.

* The trophon technology of sonically activated hydrogen peroxide is used by both the trophon2 and trophon EPR to achieve HLD

With over 22,500 trophon units operating worldwide, approximately 75,000 people each day are protected from the risk of cross-contamination
Protecting more than 19 million patients every year

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Without automation, proper HLD requires hands-on technician time

While manual reprocessing of ultrasound probes and handles can satisfy requirements, it requires hands-on technician time that takes you away from other important tasks, like patient care. It also increases the technician contact time with a potentially contaminated device and the chemicals used to disinfect it. Also manual processes require manual record keeping, lacking standardization and traceability.

Because of the superior reliability and reproducibility of automated methods such as trophon2, many guidelines around the world now specify automation as the preferred disinfection process.1-15 This automation allows trophon2 to provide reliable, documented HLD efficacy with every cycle.

  • Digital traceability (RFID technology – AcuTrace) automatically records the operator, probe and cycle data to capture and demonstrate compliance.
  • Records are ready for audits without compromising time or level of detail.
  • trophon2 simplifies and reduces workflow burden at point of use

    trophon2 requires less than 2 minutes of your time to run a 7 minute HLD cycle, giving you the confidence to get on with other important tasks without compromising reprocessing efficacy.

Even before the COVID-19 pandemic, patient cross contamination from ultrasound probes represented a risk
If effective high-level disinfection (HLD) of both the probe and handle is not performed after use, there is a risk of patient-to-patient transmission, potentially causing serious infections.2-9

In 2017, the largest population study ever performed on ultrasound transmission risk demonstrated the significantly increased risk of patient cross-contamination via ultrasound procedures.2 With routine transvaginal (TV) ultrasounds, patients were 41% more likely to have positive bacterial cultures and 26% more likely to have been prescribed antibiotics in the 30 days following compared to matched controls.2 This occurred during a period where the majority of institutions were performing low-level disinfection (LLD) of these probes.2 The national authority (Scotland) has since recommended HLD for all semi-critical procedures including TV probes regardless of sheath use.10

Patients who had an ultrasound procedure were 41% more likely to acquire an infection when low-level disinfection (LLD) was the preferred disinfection method.2

That’s why infection prevention continues to be on the critical agenda for healthcare institutions and practitioners. Of course, never more so than today as we look to manage the 2019 coronavirus disease (COVID-19) crisis. Proper reprocessing of reusable medical devices, including ultrasound probes, is an important tool in your arsenal to reduce the risk of transmission.

Ultrasound is an important tool for COVID-19 diagnosis and patient care
Ultrasound is a useful clinical tool in assessing and treating patients, including those with viral pneumonia (a feature of COVID-19). It can be used to monitor the degree of fluid build-up in the lungs (lung ultrasound) and to guide procedures in the removal of that fluid (thoracentesis),11,12 or be used for ultrasound-guided vascular access.

It is possible that through clinical use, medical equipment, including ultrasound probes may become contaminated with severe acute respiratory syndrome (SARS-CoV-2), the virus that causes COVID-19. This may be in the acute setting when performing procedures on symptomatic patients, but may also occur in other healthcare settings from patients who are in the presymptomatic phase of the disease. No matter how and where you perform ultrasound procedures, to make ultrasound as safe as possible, preventing the spread of the virus and protection of healthcare workers is paramount.13

The risk of encountering COVID-19 is not limited to those with positive COVID-19 test results

The SARS-CoV-2 virus emerged as a novel coronavirus in December 2019 and can spread from person-to-person via contact with respiratory droplets from an infected person.14

Due to the recent emergence of the virus, trophon2 has not been tested directly against SARS-CoV-2. However, SARS-CoV-2 is an enveloped virus and trophon2 is effective against both enveloped viruses and non-enveloped viruses, Read more.

High-level disinfection (HLD) is an important tool to prevent the spread of infection
High-level disinfection (HLD) is an important tool to prevent the spread of infection

Since the 1960s, the Spaulding classification has been the tool that helps define how an object should be disinfected. Sterilization and disinfection guidelines for medical devices and instruments worldwide recommend that semi-critical objects, like ultrasound probes, that touch mucous membranes or non-intact skin should be high-level disinfected.15 High-level disinfection (HLD) is the complete elimination of all microorganisms from a medical device, such as an ultrasound probe, except for small numbers of bacterial spores.15 That means HLD ultrasound probe reprocessing must be effective against enveloped and non-enveloped viruses, vegetative bacteria, fungi and mycobacteria.15

trophon2, as an HLD device, offers the broadest microbial efficacy spectrum across the widest range of microbial species, including enveloped and non-enveloped viruses.

trophon technology has been demonstrated to be effective against the following micro-organisms.

Full range of organisms trophon has been tested against
Vegetative bacteria
Carbapenem-resistant Escherichia coli
Enterococcus hirae
Methicillin-resistant Staphylococcus aureus
Neisseria gonorrhoea
Pseudomonas aeruginosa
Staphylococcus aureus
Vancomycin-resistant enterococcus
Mycobacterium terrae
Mycobacterium avium
Bacterial endospores
Bacillus cereus
Bacillus subtilis subsp. spizizenii
Geobacillus stearothermophilus
Clostridium difficile
Candida albicans
Aspergillus brasiliensis (niger)
Adenovirus type 5 strain adenoid 75
Hepatitis A
Duck Hepatitis B virus
(surrogate virus for Human Hepatitis B virus)
Bovine Viral Diarrhoea virus Oregon
(surrogate for Human Hepatitis C virus)
Herpes Simplex Virus Type 1
Human Immunodeficiency Virus Type 1
Human Papillomavirus (HPV) 16 and 18
Murine parvovirus (Minute virus of Mice)
Poliovirus Type 1
Polyomavirus simian virus 40 (SV40)
Feline Calicivirus (surrogate for norovirus)
Murine norovirus Berlin 06/06/DE
Vaccinia virus strain Elstree

trophon has been shown to inactivate these pathogens in laboratory tests.


Finally trophon2 is tested, approved and endorsed by ultrasound manufacturers as offering the reprocessing standard of care

Finally trophon2 is tested, approved and endorsed by ultrasound manufacturers as offering the reprocessing standard of care

trophon2 is the reprocessing solution of choice for 22 US manufacturers, included in the instructions for use (IFU) of over 1,000 probes.

HLD: high-level disinfection –bactericidal, mycobacterial, fungicidal and virucidal disinfection.
  1. Nyhsen CM, et al Insights into Imaging. 2017;8(6):523-35.
  2. Scott D, et al. Ultrasound 2018;26(3):168-177.
  3. Medicines and Healthcare products Regulation Agency. Reusable transoesophageal echocardiography, transvaginal and transrectal ultrasound probes (transducers) Document: MDA/2012/037.
  4. Alfa, M.J. Infect Control Hosp Epidemiol 2015; 36: 585–586
  5. Ngu A, et al. Infect Control Hosp Epidemiol 2015;36(5):581–584.
  6. Buescher DL, et al. Ultrasound Obstet Gynecol 2016;47(5): 646-651.
  7. Leroy S. J Hosp Infect 2013;83(2):99-106.
  8. Ma ST, et al. Emerg Med J 2013;30(6):472-475.
  9. Oide S, et al. J Med Ultrason (2001) 2019;46(4):475-479.
  10. Health Protection Scotland (HPS), Health Facitlities Scotland (HFS), National Services Scotland (NHS). NHSScotland Guidance for Decontamination of Semi-Critical Ultrasound Probes; Semi-invasive and Non-invasive Ultrasound Probes. 2016
  11. Shi H, et al. Lancet Infect Dis;
  12. Soni N, et al. J Hosp Med 2015;10(12):811-816.
  13. Poon LC, et al. Ultrasound Obstet Gynecol 2020;doi:10.1002/uog.22027.
  14. World Health Organization. Q&A on coronaviruses (COVID-19). Available at: (accessed 30 March 2020).
  15. Centers for Disease Control and Prevention. Guideline for disinfection and sterilisation in healthcare facilities. Available at: (accessed 30 March 2020).